Original Communications:

Hidetoshi Nagayoshi, Kazuhiko Fukatsu, Chikara Ueno, Etsuko Hara, Yoshinori Maeshima, Jiro Omata, Hoshio Hiraide, and Hidetaka Mochizuki

5-Fluorouracil Infusion Reduces Gut-Associated Lymphoid Tissue Cell Number and Mucosal Immunoglobulin A Levels
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 395-400. [Abstract] [Full Text] [PDF]  
Mice received continuous IV infusion of normal saline or 10 mg/kg of 5-fluorouracil (5-FU) for 5 days. Despite no differences in body weight changes or food intake, gut-associated lymphoid tissue cell numbers and mucosal IgA levels were lower in the 5-FU than the control group.

Hong-Shiee Lai, Wen-His Lin, Pey-Rong Chen, Hsiu-Chuan Wu, Po-Huang Lee, and Wei-Jao Chen

Effects of a High-Fiber Diet on Hepatocyte Apoptosis and Liver Regeneration After Partial Hepatectomy in Rats With Fatty Liver
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 401-407. [Abstract] [Full Text] [PDF]  
Fatty liver can be induced by a high-fat diet and may increase the apoptosis of hepatocytes and decrease liver regeneration after partial hepatectomy. A high-fiber diet can reverse fatty liver and reverse the negative effects of fatty liver on apoptosis and liver regeneration.

Albert Chang, Robert Enns, Olivia Saqui, Nazira Chatur, Scott Whittaker, and Johane P. Allard

Line Sepsis in Home Parenteral Nutrition Patients: Are There Socioeconomic Risk Factors? A Canadian Study
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 408-412. [Abstract] [Full Text] [PDF]  
Socioeconomic risk factors were identified for line sepsis in home parenteral nutrition (PN) patients. A comparison between 2 different home PN programs revealed no differences in line sepsis.

Evelyn B. Enrione, Barbara Thomlison, and Aviva Rubin

Medical and Psychosocial Experiences of Family Caregivers With Children Fed Enterally at Home
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 413-419. [Abstract] [Full Text] [PDF]  
Caregivers rated medical and psychosocial situations to determine which were most frequent and difficult. The psychosocial problems were perceived as a greater concern, more of a burden, and causing greater difficulty in coping with everyday life.

Lorri M. Phipps, Mark D. Weber, Beth R. Ginder, Michael A. Hulse, and Neal J. Thomas

A Randomized Controlled Trial Comparing Three Different Techniques of Nasojejunal Feeding Tube Placement in Critically Ill Children
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 420-424. [Abstract] [Full Text] [PDF]  
Although several authors have found moderate success with more complicated and potentially harmful procedures, we have demonstrated in the first randomized controlled trial comparing 3 commonly used techniques an equivocal success rate using nothing more than consistent practice techniques and experienced clinicians.

Mark H. DeLegge, Gregory Borak, and Nicole Moore

Central Venous Access in the Home Parenteral Nutrition Population–You PICC
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 425-428. [Abstract] [Full Text] [PDF]  
Home parenteral nutrition (HPN) is a commonly prescribed therapy. Peripherally inserted central catheters (PICC) are being used more frequently for HPN delivery. A retrospective analysis of PICC versus other central venous access devices for the delivery of HPN revealed an increase in catheter-related infections in the PICC group.

Roland N. Dickerson, Darius L. Mason, Martin A. Croce, Gayle Minard, and Rex O. Brown

Evaluation of an Artificial Neural Network to Predict Urea Nitrogen Appearance for Critically Ill Multiple-Trauma Patients
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 429-435. [Abstract] [Full Text] [PDF]  
These preliminary data indicate that a computer-based artificial intelligence network may be more accurate for estimating extent of protein catabolism than conventional mathematical modeling in critically ill patients.

Roland N. Dickerson, Laurie G. Morgan, April D. Cauthen, Kathryn H. Alexander, Martin A. Croce, Gayle Minard, and Rex O. Brown

Treatment of Acute Hypocalcemia in Critically Ill Multiple-Trauma Patients
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 436-441. [Abstract] [Full Text] [PDF]  
The efficacy of an IV graduated calcium gluconate dosing regimen for hypocalcemia was examined in 37 trauma intensive care unit patients. One to 2 g was successful in 79% of patients with mild hypocalcemia (ionized calcium: 1–1.12 mmol/L); 2–4 g was successful for 38% of patients with moderate to severe hypocalcemia.

Alison Saalwachter Schulman and Robert G. Sawyer

The Safety of Percutaneous Endoscopic Gastrostomy Tube Placement in Patients With Existing Ventriculoperitoneal Shunts
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 442-444. [Abstract] [Full Text] [PDF]  
Due to potential contamination with enteric contents, patients are theoretically at increased risk for meningitis. In this series of 39 patients, we did not find an increased rate of infection for shunted patients after percutaneous endoscopic gastrostomy placement compared to previously published shunt infection rates.

M. A. Martínez Olmos, M. J. Martínez Vázquez, M. J. Morales Gorría, P. Parada González, I. Otero Martínez, I. Maruri Chimeno, E. Pena González, M. T. Inaraja Bobo, and J. E. Casal Núñez

Effect of Parenteral Nutrition on Nutrition Status After Bariatric Surgery for Morbid Obesity
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 445-450. [Abstract] [Full Text] [PDF]  
We evaluate the influence of nutrition support in 67 consecutive bariatric surgery patients. Postoperative and 30 days postsurgery nutrition status was similar with or without parenteral nutrition; postsurgery hospital stay significantly decreased in the latter without greater complications. Parenteral nutrition seems unnecessary in bariatric surgery unless there are other complications.

Brief Communications:

James S. Scolapio, Marcus Ferrone, and Robert A. Gillham

Urticaria Associated With Parenteral Nutrition
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 451-453. [Abstract] [Full Text] [PDF]  
Infusion of PN can rarely be associated with allergic reactions including urticaria. In this case we illustrate a patient who developed urticaria during infusion of PN containing a multivitamin preparation.

Letters to the Editor:

Lydia Fairholm, Olivia Saqui, Mary Baun, Johane Allard, Darlene G. Kelly, Lourdes Piña de la Vega, John C. Lieske, and Dawn Milliner

To the Editor:
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 454. [Full Text] [PDF]  

Azeez Farooki

To the Editor:
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 455. [Full Text] [PDF]  

Editorials:

Charles W. Van Way, III

Socioeconomic Effects on Home Parenteral Nutrition
(SAGE) JPEN J Parenter Enteral Nutr 2005 29: 456-457. [Full Text] [PDF]  

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