Journal Article:

YY Wang, HF Shang, YN Lai, and SL Yeh

Arginine supplementation enhances peritoneal macrophage phagocytic activity in rats with gut-derived sepsis
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 235-240. [Abstract] [PDF]  
Enteral arginine supplementation before sepsis enhances macrophage phagocytic activity and reduces bacteria numbers in peritoneal lavage fluid. Arginine administered before and after sepsis has a synergistic effect on enhancing phagocytosis and on bacterial clearance. However, intravenous arginine administration after sepsis had no favorable effects on phagocytic activity or survival rates in gut-derived sepsis.

A Dhar, S Kujath, and CW Van Way, III

Glutamine administration during total parenteral nutrition protects liver adenosine nucleotides during and after subsequent hemorrhagic shock
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 246-251. [Abstract] [PDF]  
Before experimental hemorrhagic shock in rats, total parenteral nutrition with and without glutamine was given for 7 days. Hepatic adenosine nucleotides were measured with high-performance liquid chromatography. The glutamine-treated animals lost less adenosine triphosphate during shock and recovered more quickly after resuscitation.

GM Rovera, RE Schoen, B Goldbach, D Janson, G Bond, J Rakela, TO Graham, S O'Keefe, and K Abu-Elmagd

Intestinal and multivisceral transplantation: dynamics of nutritional management and functional autonomy
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 252-259. [Abstract] [PDF]  
The nutritional status and allograft absorptive functions were monitored during the first 12 postoperative months in 22 intestinal recipients. By the first month, all patients tolerated enteral feeding, and by 6 months, 73% had discontinued total parenteral nutrition. With long-term follow-up, most of the engrafted intestines restored the nutritional autonomy, and all survivors remained well nourished.

ME Houdijk, MT Engelbregt, C Popp-Snijders, and HA Delemarre van der Waal

Long-term effects of early postnatal food restriction on growth hormone secretion in rats
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 260-267. [Abstract] [PDF]  
Food restriction (FR) during lactation, leading to incomplete catchup growth in adult female and male rats (mean age, 3.5 months), significantly increases baseline rGH secretion and reduces serum IGF-I concentrations in the adult male FR rat compared with control rats receiving a normal food intake during lactation.

JN Zuercher, EJ Cumella, BK Woods, M Eberly, and JK Carr

Efficacy of voluntary nasogastric tube feeding in female inpatients with anorexia nervosa
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 268-276. [Abstract] [PDF]  
Patients receiving tube feeding in addition to oral refeeding gained more weight per treatment week than those receiving oral refeeding alone. There were no differences between patient groups in recovery from the psychologic aspects of anorexia or the frequency of medical complications.

T Abell, J Lou, M Tabbaa, O Batista, S Malinowski, and A Al-Juburi

Gastric electrical stimulation for gastroparesis improves nutritional parameters at short, intermediate, and long-term follow-up
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 277-281. [Abstract] [PDF]  
Gastric electrical stimulation for patients with drug-refractory gastroparesis improves gastrointestinal symptoms, patient weight and body mass index, nutritional laboratory characteristics, and health-related quality-of-life measures.

JF Simmons, A Skipper, LJ Lafferty, and MB Gregoire

A survey of perceived benefit and differences in therapy provided by credentialed and noncredentialed nutrition support dietitians
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 282-286. [Abstract] [PDF]  
A survey of credentialed and noncredentialed nutrition support dietitians revealed that Certified Nutrition Support Dietitians are generally satisfied with benefits of being credentialed. Differences were identified in cost of therapy but not in monitoring or time spent in assessing patients.

KA Kudsk, SK Reddy, GS Sacks, and HC Lai

Joint Commission for Accreditation of Health Care Organizations guidelines: too late to intervene for nutritionally at-risk surgical patients
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 288-290. [Abstract] [PDF]  
The current Joint Commission for Accreditation of Health Care Organizations guidelines do not allow early identification of malnourished patients who might benefit from preoperative nutrition support because such a large number of them undergo surgery on the day of admission.

Clinical Trial:

YP Zhou, ZM Jiang, YH Sun, XR Wang, EL Ma, and D Wilmore

The effect of supplemental enteral glutamine on plasma levels, gut function, and outcome in severe burns: a randomized, double-blind, controlled clinical trial
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 241-245. [Abstract] [PDF]  
The supplementation of enteral alanyl-glutamine dipeptide for 12 days after severe burn injury at a dose of 0.5g/kg/day in 20 patients supported plasma glutamine levels, improved gut permeability, and initially decreased plasma endotoxin levels. These results were compared with those of patients not receiving glutamine dipeptide supplementation.

Comment:

Cost and clinical effectiveness of certification cannot be measured using survey methods
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 287. [PDF]  
This commentary maintains that the survey research methods used in the article by Furman Simmons et al cannot evaluate health care costs or the effectiveness of clinical care. These outcomes are appropriately evaluated by outcome research or clinical epidemiology. Health care professionals and administrators should not regard the results of the Furman Simmons et al survey as valid.

J Wernerman

Glutamine to intensive care unit patients
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 302-303. [PDF]  

Jonathan Rhoads Symposium Papers:

SJ Dudrick

Early developments and clinical applications of total parenteral nutrition
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 291-299. [Abstract] [PDF]  
A historical account of the status of surgical nutrition 4 decades ago; the seminal laboratory studies culminating in the first effective long-term total parenteral nutrition technique, manifested by growth and development of intravenously fed puppies; and the subsequent successful clinical applications of the basic methodology to the nutrition support of critically ill pediatric and adult patients are summarized.

Editorials:

CW Van Way, III

The price of quality
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 300-301. [PDF]  

Case Reports:

JM Guardino, JK Hix, and D Seidner

A case of hypokalemia and rhabdomyolysis in a patient with short bowel syndrome
(SAGE) JPEN J Parenter Enteral Nutr 2003 27: 305. [PDF]  

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