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Selenium and Vitamin E Stability in Parenteral Solutions
C.D. Mcgee, B.A.SC.
Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, Department of Pharmacy, Toronto General Hospital, Toronto, Canada
M.G. Mascarenhas, B.SC.PHM.
Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, Department of Pharmacy, Toronto General Hospital, Toronto, Canada
M.J. Ostro, M.D.
Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, Department of Pharmacy, Toronto General Hospital, Toronto, Canada
G. Tsallas, B.SC.PHM.
Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, Department of Pharmacy, Toronto General Hospital, Toronto, Canada
K.N. Jeejeebhoy, M.B., B.S., PH.D.
Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, Department of Pharmacy, Toronto General Hospital, Toronto, Canada
Stability of -tocopherol acetate and selenium in amino acid/dextrose solutions with SoluZyme or MVI-1000 vitamin injections was evaluated following exposure to fluorescent lighting and room temperature, and after flowing through an infusion apparatus. The stability of selenium in parenteral solutions for a 10-wk period was also determined. In each condition no significant loss of -tocopherol acetate or selenium was observed. It was concluded that -tocopherol acetate and selenium as selenious acid are stable in parenteral solutions and no significant loss occurs during delivery to patients. (Journal of Parenteral and Enteral Nutrition 9:568-570, 1985)
Journal of Parenteral and Enteral Nutrition, Vol. 9, No. 5,
568-570 (1985)
DOI: 10.1177/0148607185009005568

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