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Use of Thyroxine-binding Prealbumin in the Nutritional Assessment of Children with Cancer

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

Diane Carr, MPH, R.D.

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

Jan Van Eys, PH.D., M.D.

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

Patricia Carter, R.D.

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

Irma Ramirez, M.D.

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

Grant Taylor, M.D.

Department of Pediatrics, The University of Texas, M. D. Anderson Hospital and Tumor Institute. Houston, Texas

The level of thyroxine-binding prealbumin was evaluated in 87 pediatric cancer patients ages 1 through 16 years whose cancer was newly diagnosed but untreated, and 39 children with benign disease or no disease. There was no difference in levels of thyroxine-binding prealbumin between the patients with either malignant or benign disease, nor was there a difference between diagnostic categories. Prealbumin values did correlate with age. When the data were compared, there was a correlation between nutritional status and prealbumin level when the total population (N = 126) was age corrected, but not within the malignant disease group by itself. This confirms data that suggest malnutrition in children with cancer is not a result of protein depletion.

Journal of Parenteral and Enteral Nutrition, Vol. 7, No. 2, 151-153 (1983)
DOI: 10.1177/0148607183007002151


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