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Journal of Parenteral and Enteral Nutrition
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Case Reports

Parenteral Nutrition in Anuria of Infancy: Evidence for Sustained Net Protein Synthesis

Jukka Takala, M.D.

Departments of Anesthesiology and Pediatric Surgery, Turku University Central Hospital, Turku, Finland

Martti Kekomäki, M.D.

Departments of Anesthesiology and Pediatric Surgery, Turku University Central Hospital, Turku, Finland

The effects of total parenteral nutrition were studied in two anuric neonates and an anuric infant. Based on the observations of urea production, nitrogen balance, and serum osmolality, the bulk of the infused nitrogen appeared to be incorporated into the body proteins. The need for potassium, calcium, phosphorous, and magnesium substitution was also indicative of net anabolism. Despite effective utilization of the amino acids, high plasma levels of phenylalanine and methionine, and extremely low levels of the urea cycle intermediates were measured. We conclude that the application of carefully planned parenteral nutrition may aid in the management of newborns with failing kidneys and that it influences considerably the indications of dialysis in early infancy.

Journal of Parenteral and Enteral Nutrition, Vol. 7, No. 1, 45-49 (1983)
DOI: 10.1177/014860718300700145
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This article has been cited by other articles:


Home page
 Arch Pediatr Adolesc MedHome page
G. P. Giacoia, R. Miranda, and K. I. West
Measured vs Calculated Plasma Osmolality in Infants With Very Low Birth Weights
Arch Pediatr Adolesc Med, June 1, 1992; 146(6): 712 - 717.
[Abstract] [PDF]