This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Huston, R. K. Articles by Neerhout, R. C. Search for Related Content PubMed PubMed Citation Articles by Huston, R. K. Articles by Neerhout, R. C. Social Bookmarking                         What's this?

Selenium and Vitamin E Sufficiency in Premature Infants Requiring Total Parenteral Nutrition

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

Gerda I. Benda, M.D.

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

Christina V. Carlson, B.S.

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

Thomas R. Shearer, PH.D.

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

John W. Reynolds, M.D.

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

Robert C. Neerhout, M.D.

Department of Pediatrics, School of Medicine, Department of Biochemistry, School of Dentistry, Oregon Health Sciences University, Portland, Oregon

A randomized prospective study of LBW infants was undertaken to evaluate the effect of parenteral lipid infusions upon their antioxidant systems. Ten babies received a parenteral nutrition regimen with lipid emulsion, and ten received a regimen without lipid. Although the addition of lipid emulsion to the total parenteral nutrition regimen led to a rise in vitamin E levels, the selenium levels fell in both groups. Neither group showed evidence of deficient antioxidant systems by the peroxide hemolysis test or thiobarbituric acid test. There did not seem to be any adverse effect of the lipid infusion upon the clinical course of the infants except for hyperlipidemia. There was a better weight gain in infants receiving lipid.

Journal of Parenteral and Enteral Nutrition, Vol. 6, No. 6, 507-510 (1982)
DOI: 10.1177/0148607182006006507


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				R. K. Huston, B. J. Jelen, and J. Vidgoff Selenium Supplementation in Low-Birthweight Premature Infants: Relationship to Trace Metals and Antioxidant Enzymes JPEN J Parenter Enteral Nutr, September 1, 1991; 15(5): 556 - 559. [Abstract] [PDF]

				R. K. Huston, T. R. Shearer, B. J. Jelen, P. D. Whall, and J. W. Reynolds Relationship of Antioxidant Enzymes to Trace Metals in Premature Infants JPEN J Parenter Enteral Nutr, March 1, 1987; 11(2): 163 - 168. [Abstract] [PDF]

				V. Devito, J. W. Reynolds, G. I. Benda, and C. Carlson Serum Vitamin E Levels in Very Low-Birth Weight Infants Receiving Vitamin E in Parenteral Nutrition Solutions JPEN J Parenter Enteral Nutr, January 1, 1986; 10(1): 63 - 65. [Abstract] [PDF]

				G. R. Gutcher, A. A. Lax, and P. M. Farrell Tocopherol Isomers in Intravenous Lipid Emulsions and Resultant Plasma Concentrations JPEN J Parenter Enteral Nutr, May 1, 1984; 8(3): 269 - 273. [Abstract] [PDF]