This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Van Rij, A. M. Articles by Robinson, M. F. Search for Related Content PubMed PubMed Citation Articles by Van Rij, A. M. Articles by Robinson, M. F. Social Bookmarking                         What's this?

Selenium Supplementation in Total Parenteral Nutrition

Department of Surgery, School of Medicine, Department of Nutrition, School of Home Science, Otago University, Dunedin, New Zealand

Joan M. Mckenzie, PH.D.

Department of Surgery, School of Medicine, Department of Nutrition, School of Home Science, Otago University, Dunedin, New Zealand

Christine D. Thomson, PH.D.

Department of Surgery, School of Medicine, Department of Nutrition, School of Home Science, Otago University, Dunedin, New Zealand

Marion F. Robinson, PH.D.

Department of Surgery, School of Medicine, Department of Nutrition, School of Home Science, Otago University, Dunedin, New Zealand

Four adult patients with very low plasma selenium (Se) levels (1.5 µg/100 ml) were given Se supplements while receiving total parenteral nutrition. A comparison was made using the compounds selenomethionine and sodium selenite given either intravenously or by mouth. Urinary excretion and Se plasma responses differed, and indicated that selenomethionine retention was greater. However, the incorporation of Se into the erythrocyte and its enzyme glutathione peroxidase was unpredictable and delayed and was not a good indicator of supplement response. No deleterious effects of supplements were observed. Se supplements are indicated especially in patients with a high risk of developing low Se levels and are best monitored by plasma Se levels.

Journal of Parenteral and Enteral Nutrition, Vol. 5, No. 2, 120-124 (1981)
DOI: 10.1177/0148607181005002120


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				H. H. Zhang, Z. F. Wu, C. L. Yang, B. Xia, D. R. Xu, and H. X. Yuan Spatial Distributions and Potential Risk Analysis of Total Soil Selenium in Guangdong Province, China J. Environ. Qual., May 1, 2008; 37(3): 780 - 787. [Abstract] [Full Text] [PDF]

				A. H. Verhage, W. K. Cheong, and K. N. Jeejeebhoy Neurologic Symptoms Due to Possible Chromium Deficiency in Long-Term Parenteral Nutrition That Closely Mimic Metronidazole-Induced Syndromes JPEN J Parenter Enteral Nutr, March 1, 1996; 20(2): 123 - 127. [Abstract] [PDF]

				C.K. Abrams, S.M. Siram, C. Galsim, H. Johnson-Hamilton, F.L. Munford, and H. Mezghebe Selenium Deficiency in Long-Term Total Parenteral Nutrition Nutr Clin Pract, August 1, 1992; 7(4): 175 - 178. [Abstract] [PDF]

				K. Sando, M. Hoki, R. Nezu, Y. Takagi, and A. Okada Platelet Glutathione Peroxidase Activity in Long-Term Total Parenteral Nutrition With and Without Selenium Supplementation JPEN J Parenter Enteral Nutr, January 1, 1992; 16(1): 54 - 58. [Abstract] [PDF]

				W. C. Reeves, S. P. Marcuard, S. E. Willis, and A. Movahed Reversible Cardiomyopathy Due to Selenium Deficiency JPEN J Parenter Enteral Nutr, November 1, 1989; 13(6): 663 - 665. [Abstract] [PDF]

				H. W. Lane, C. A. Lotspeich, C. E. Moore, J. Ballard, S. J. Dudrick, and D. C. Warren The Effect of Selenium Supplementation on Selenium Status of Patients Receiving Chronic Total Parenteral Nutrition JPEN J Parenter Enteral Nutr, March 1, 1987; 11(2): 177 - 182. [Abstract] [PDF]

				R. J. Baptista, B. R. Bistrian, G. L. Blackburn, D. G. Miller, C. D. Champagne, and L. Buchanan Suboptimal Selenium Status in Home Parenteral Nutrition Patients with Small Bowel Resections JPEN J Parenter Enteral Nutr, September 1, 1984; 8(5): 542 - 545. [Abstract] [PDF]

				H. W. Lane, A. O. Barroso, D. Englert, S. J. Dudrick, and B. S. Macfadyen JR Selenium Status of Seven Chronic Intravenous Hyperalimentation Patients JPEN J Parenter Enteral Nutr, September 1, 1982; 6(5): 426 - 431. [Abstract] [PDF]