Parenteral Nutrition Prolongs the Survival of Patients Associated With Malignant Gastrointestinal ObstructionFrom the Department of Surgery, Wenzhou Medical College, Taizhou Hospital, Zhejiang, China Correspondence: Bo-Guang Fan, MD, PhD, Department of Surgery, Taizhou Hospital of Zhejiang Province, Taizhou Linhai, Zhejiang Province, China. Electronic mail may be sent to fanboguang{at}gmail.com.
Background: Many patients with advanced cancers have associated
gastrointestinal (GI) obstruction. Parenteral nutrition (PN) is indicated in
patients with a dysfunctional GI tract, but the role of PN in patients'
survival is still controversial. The present study was retrospectively
conducted to verify if there are any long-term survivors living for more than
1 year after initiation of PN without food or drink in patients with malignant
GI tract obstruction resulting from advanced cancers. Methods: One
hundred fifteen adult patients with malignant GI obstruction were identified
over a 6-year period at a palliative-care setting. Their median age was 51
years (range, 31–74 years), and 62 (54%) were women and 53 men (46%).
All selected patients had malignant GI tract obstruction and started PN
treatment after cessation of energy intake to time of death. Survival
expectancy as a criterion was analyzed in all patients. Results: The
median time from initiation of PN to death was 6.5 months. Eleven patients
survived
Journal of Parenteral and Enteral Nutrition, Vol. 31, No. 6,
508-510 (2007) |
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1 year and 2 patients have been alive for almost 4 years later
after cessation of energy intake. Conclusions: PN can be expected to
obtain a longer survival for the patient with GI tract obstruction caused by
advanced cancer.