This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Hauser, B. Articles by Vandenplas, Y. Search for Related Content PubMed PubMed Citation Articles by Hauser, B. Articles by Vandenplas, Y. Social Bookmarking                         What's this?

Plasma Amino Acid Concentrations in Term-Born Infants Fed a Whey Predominant or a Whey Hydrolysate Formula

Department of Pediatrics, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium

U. Blecker

Department of Pediatrics, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium, Department of Pediatrics, LSU Medical Center, New Orleans

K. Keymolen

Department of Pediatrics, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium

B. Suys

Department of Pediatrics, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium

E. Gerlo

Department of Clinical Chemistry, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium

Y. Vandenplas

Department of Pediatrics, Academisch Ziekenhuis Kinderen, Vrije Universiteit Brussel, Brussels, Belgium

Background: Hydrolysates are used in the treatment and prevention of cow's milk protein allergy. Hydrolysis might alter the plasma level of amino acids. Methods: Forty-five infants were included in a double-blind prospective study and were randomized in two groups: one receiving a whey predominant formula (n = 20) and the second group receiving a whey hydrolysate formula (n = 25). Weight and length gain was evaluated up to the age of 13 weeks, when blood was sampled for determination of fasting plasma amino acids. Results: Four infants of the hydrolysate group dropped out because refusal to ingest the formula. Weight and length gain at 13 weeks of age were extremely comparable. Significant differences in plasma concentrations were observed for a number of nonessential and essential amino acids ( p = .035 to .0001). Threonine and lysine were both higher in the hydrolysate group, and aspartic acid, cystine, methionine, tyrosine, phenylalanine, histidine, and arginine were lower in the hydrolysate group. Conclusions: These differences in plasma amino acid levels have to be regarded with care because all concentrations were within normal ranges, with the exception of threonine. Weight and length gain of the hydrolysate and the whey predominant formula were identical. (Journal of Parenteral and Enteral Nutrition 21: 027-030, 1997)

Journal of Parenteral and Enteral Nutrition, Vol. 21, No. 1, 27-30 (1997)
DOI: 10.1177/014860719702100127


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				O. Hernell and B. Lonnerdal Nutritional evaluation of protein hydrolysate formulas in healthy term infants: plasma amino acids, hematology, and trace elements Am. J. Clinical Nutrition, August 1, 2003; 78(2): 296 - 301. [Abstract] [Full Text] [PDF]