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Journal of Parenteral and Enteral Nutrition
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Clinical Trial

Does Perioperative Total Parenteral Nutrition Reduce Medical Care Costs?

John M. Eisenberg, MD

Section of General Internal Medicine (Department of Medicine), Department of Surgery, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia Department of Veterans Affairs Medical Center, Department of Veterans Affairs Medical Research Service, Department of Cooperative Studies Program, Perry Point, Maryland

Henry A. Glick, MA

Section of General Internal Medicine (Department of Medicine), Department of Surgery, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia Department of Veterans Affairs Medical Center, Department of Veterans Affairs Medical Research Service, Department of Cooperative Studies Program, Perry Point, Maryland

Gordon P. Buzby, MD

Section of General Internal Medicine (Department of Medicine), Department of Surgery, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia Department of Veterans Affairs Medical Center, Department of Veterans Affairs Medical Research Service, Department of Cooperative Studies Program, Perry Point, Maryland

Bruce Kinosian, MD

Section of General Internal Medicine (Department of Medicine), Department of Surgery, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia Department of Veterans Affairs Medical Center, Department of Veterans Affairs Medical Research Service, Department of Cooperative Studies Program, Perry Point, Maryland

William O. Williford, PHD

Section of General Internal Medicine (Department of Medicine), Department of Surgery, and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia Department of Veterans Affairs Medical Center, Department of Veterans Affairs Medical Research Service, Department of Cooperative Studies Program, Perry Point, Maryland

An economic analysis accompanied a multicenter Department of Veterans Affairs randomized, controlled trial of perioperative total parenteral nutrition (TPN). The cost of providing TPN for an average of 16.15 days before and after surgery was $2405, more than half of which ($1025) included costs of purchasing, preparing, and delivering the TPN solution itself; lipid solutions accounted for another $181, additional nursing care for $843, and miscellaneous costs for $356. Prolonged hospital stay added another $764 per patient to the $2405 cost of providing TPN, bringing the total to $3169. The incremental costs attributed to perioperative TPN were highest ($3921) for the patients least likely to benefit, that is, those who were less malnourished and at low risk of nutrition-related complications. Incremental costs were lowest ($3071) for high-risk patients. On the basis of the hospital-based method of administering TPN that was used in the clinical trial, perioperative TPN did not result in decreased costs for any subgroup of patients. (Journal of Parenteral and Enteral Nutrition 17:201-209, 1993)

Journal of Parenteral and Enteral Nutrition, Vol. 17, No. 3, 201-209 (1993)
DOI: 10.1177/0148607193017003201


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