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Selenium Deficiency and Cardiomyopathy in Acquired Immunodeficiency Syndrome

Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

Andrea Ruff, M.D.

Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

Elizabeth Perlman, M.D.

Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland

Nancy Hutton, M.D.

Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

John Modlin, M.D.

Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

Stuart Rowe, M.D.

Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, Maryland

Selenium deficiency is common in patients with human immunodeficiency virus infection and may contribute to the development of cardiomyopathy. A 5-year-old boy with congenital human immunodeficiency virus infection developed cardiomyopathy. Evaluation for reversible causes of cardiomyopathy was notable for the diagnosis of selenium deficiency. Cardiac function improved on selenium supplementation. The role of selenium in cardiac dysfunction and the need for nutritional evaluation and supplementation of malnourished patients with acquired immunodeficiency syndrome is discussed. (Journal of Parenteral and Enteral Nutrition 15:347-349,1991)

Journal of Parenteral and Enteral Nutrition, Vol. 15, No. 3, 347-349 (1991)
DOI: 10.1177/0148607191015003347


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