Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Parenteral and Enteral Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Oriot, D.
Right arrow Articles by Huault, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Oriot, D.
Right arrow Articles by Huault, G.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Hazardous Substances DB
*VITAMIN B1
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Case Reports

Severe Lactic Acidosis Related to Acute Thiamine Deficiency

Denis Oriot, M.D.

Division of Pediatric Intensive Care, Montreal Children's Hospital, Department of Pediatrics, McGill University, Montreal, Quebec, Canada

Chantal Wood, M.D.

Réanimation Pédiatrique, Hôpital de Bicêtre, France

Ronald Gottesman, M.D.

Division of Pediatric Intensive Care, Montreal Children's Hospital, Department of Pediatrics, McGill University, Montreal, Quebec, Canada

Gilbert Huault, M.D., PH.D.

Réanimation Pédiatrique, Hôpital de Bicêtre, France

The authors report a case of severe lactic acidosis in a 3-year-old boy, after 20 days of total parenteral nutrition without vitamin supplementation. This child with acute lymphoblastic leukemia underwent a period of severe refractory lactic acidosis (pH between 6.81 and 7.00 and a serum lactate level up to 38 mmol/liter) leading to cardiac arrest. After the initial resuscitation and the subsequent treatment of shock and vitamin K deficiency, acute peritoneal dialysis was instituted to correct the severe lactic acidosis. Initial low plasma thiamine levels confirmed the diagnosis of thiamine deficiency. An associated transient pancreatic dysfunction was also noted. The patient's overall course with thiamine replacement therapy led to a complete recovery within 5 days and no sequelae were noted after 12 months. (Journal of Parenteral and Enteral Nutrition 15:105-109, 1991)

Journal of Parenteral and Enteral Nutrition, Vol. 15, No. 1, 105-109 (1991)
DOI: 10.1177/0148607191015001105
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
K. Masumoto, G. Esumi, R. Teshiba, K. Nagata, T. Nakatsuji, Y. Nishimoto, S. Ieiri, N. Kinukawa, and T. Taguchi
Need for Thiamine in Peripheral Parenteral Nutrition After Abdominal Surgery in Children
JPEN J Parenter Enteral Nutr, July 1, 2009; 33(4): 417 - 422.
[Abstract] [Full Text] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
P. E. Molina, N. Myers, R. M. Smith, C. H. Lang, K. A. Yousef, P. G. Tepper, and N. N. Abumrad
Nutritional and Metabolic Characterization of a Thiamine-Deficient Rat Model
JPEN J Parenter Enteral Nutr, March 1, 1994; 18(2): 104 - 111.
[Abstract] [PDF]