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Journal of Parenteral and Enteral Nutrition
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Review: A Clinical Application of Exercise Physiology and Nutritional Support for the Mechanically Ventilated Patient

M. Molly Mcmahon, M.D.

Division of Endocrinology, Metabolism, and Internal Medicine, Mayo Clinic, Rochester, Minnesota

Peter N. Benotti, M.D.

Department of Surgery, New England Deaconess Hospital, Boston, Massachusetts

Bruce R. Bistrian, M.D., PH.D.

Nutrition Support Service, New England Deaconess Hospital, Boston, Massachusetts

A challenging problem facing the clinician is the management of critically ill patients in whom repeated attempts at weaning from mechanical ventilation are unsuccessful. The difficulty weaning these patients from the ventilator can be augmented in the presence of detraining of respiratory muscles, malnutrition, stress and the metabolic response to iniury, and/or immobilization. An understanding of basic concepts of established tenets of exercise physiology and of nutritional support will allow their application to respiratory muscle function with the goal of facilitating the endurance and strength of respiratory muscles needed to sustain spontaneous ventilation. (Journal of Parenteral and Enteral Nutrition 14:538-542, 1990)

Journal of Parenteral and Enteral Nutrition, Vol. 14, No. 5, 538-542 (1990)
DOI: 10.1177/0148607190014005538
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