Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Journal of Parenteral and Enteral Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Cynober, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cynober, L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Review: Amino Acid Metabolism in Thermal Burns

Luc Cynober, PH.D.

Eiochemistry Laboratory, Saint Antoine Hospital, Paris, France

Burn injury induces time-dependent variations in plasma amino acids, ie, an initial hyperaminoacidemia reflecting proteolysis in the wound areas, a decrease in gluconeogenic amino acids a consequence of excessive utilization in the liver, and a progressive return to normal. There is also a durable hyperphenylalaninemia, reflecting increased protein turnover and specific alterations of sulfur amino acids. In burned rats, the same general pattern is observed, except that glycine rather than alanine and glutamine exhibits the largest variations. Improvements in nutritional support with regard to the amino acid composition of diets are envisaged. (Journal of Parenteral and Enteral Nutrition 13:196-205, 1989)

Journal of Parenteral and Enteral Nutrition, Vol. 13, No. 2, 196-205 (1989)
DOI: 10.1177/0148607189013002196
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
C. Helies-Toussaint, C. Moinard, C. Rasmusen, I. Tabbi-Anneni, L. Cynober, and A. Grynberg
Aortic banding in rat as a model to investigate malnutrition associated with heart failure
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2005; 288(5): R1325 - R1331.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
J. Averous, A. Bruhat, S. Mordier, and P. Fafournoux
Recent Advances in the Understanding of Amino Acid Regulation of Gene Expression
J. Nutr., June 1, 2003; 133(6): 2040S - 2045.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
L. Schlegel, C. Coudray-Lucas, F. Barbut, J. Le Boucher, A. Jardel, S. Zarrabian, and L. Cynober
Bacterial Dissemination and Metabolic Changes in Rats Induced by Endotoxemia following Intestinal E. coli Overgrowth Are Reduced by Ornithine {{alpha}}-Ketoglutarate Administration
J. Nutr., December 1, 2000; 130(12): 2897 - 2902.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Gastrointest. Liver Physiol.Home page
T. M. Pawlik, R. Lohmann, W. W. Souba, and B. P. Bode
Hepatic glutamine transporter activation in burn injury: role of amino acids and phosphatidylinositol-3-kinase
Am J Physiol Gastrointest Liver Physiol, April 1, 2000; 278(4): G532 - G541.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
U. Ha and S. Jin
Expression of the soxR Gene of Pseudomonas aeruginosa Is Inducible during Infection of Burn Wounds in Mice and Is Required To Cause Efficient Bacteremia
Infect. Immun., October 1, 1999; 67(10): 5324 - 5331.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
D. A. De-Souza and L. J. Greene
Pharmacological Nutrition After Burn Injury
J. Nutr., May 1, 1998; 128(5): 797 - 803.
[Abstract] [Full Text]

Home page
 J. Biol. Chem.Home page
A. Bruhat, C. Jousse, X.-Z. Wang, D. Ron, M. Ferrara, and P. Fafournoux
Amino Acid Limitation Induces Expression of CHOP, a CCAAT/Enhancer Binding Protein-related Gene, at Both Transcriptional and Post-transcriptional Levels
J. Biol. Chem., July 11, 1997; 272(28): 17588 - 17593.
[Abstract] [Full Text] [PDF]

Home page
 Arch SurgHome page
M. Roch-Arveiller, M. Tissot, C. Coudray-Lucas, J. Fontagne, J. L. Boucher, J.-P. Giroud, and L. Cynober
Immunomodulatory Effects of Ornithine {alpha}-Ketoglutarate in Rats With Burn Injuries
Arch Surg, July 1, 1996; 131(7): 718 - 723.
[Abstract] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
M. Vaubourdolle, C. Coudray-Lucas, A. Jardel, F. Ziegler, O. G. Ekindjian, and L. Cynober
Action of Enterally Administered Ornithine {alpha}-Ketoglutarate on Protein Breakdown in Skeletal Muscle and Liver of the Burned Rat
JPEN J Parenter Enteral Nutr, September 1, 1991; 15(5): 517 - 520.
[Abstract] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
V. Lee Mermel, B. M. Wolfe, R. J. Hansen, and A. J. Clifford
Comparative Effects of Thermal and Surgical Trauma on Rat Muscle Protein Metabolism
JPEN J Parenter Enteral Nutr, March 1, 1991; 15(2): 128 - 136.
[Abstract] [PDF]