Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Journal of Parenteral and Enteral Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Glynn, M. J.
Right arrow Articles by Murray-Lyon, I. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Glynn, M. J.
Right arrow Articles by Murray-Lyon, I. M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Clinical Trial

High Lipid Parenteral Nutrition Improves Portasystemic Encephalopathy

Michael J. Glynn, M.A., M.B., M.R.C.P.

Gastrointestinal Unit and Department of Chemical Pathology, Charing Cross Hospital and Charing Cross and Westminster Medical School, London, England

Jeremy Powell-Tuck, M.D., M.R.C.P.

Gastrointestinal Unit and Department of Chemical Pathology, Charing Cross Hospital and Charing Cross and Westminster Medical School, London, England

David A. Reaveley, PHD, F.R.S.C.

Gastrointestinal Unit and Department of Chemical Pathology, Charing Cross Hospital and Charing Cross and Westminster Medical School, London, England

Iain M. Murray-Lyon, M.D., F.R.C.P., F.R.C.P. ED

Gastrointestinal Unit and Department of Chemical Pathology, Charing Cross Hospital and Charing Cross and Westminster Medical School, London, England

We have conducted a randomized double crossover study over 4 days in six parenterally fed patients with portasystemic encephalopathy (PSE) in which the nonprotein energy source of otherwise identical feeds was alternately all glucose or predominantly fat. Concentrations of plasma branched chain amino acids (BCAA), plasma insulin, and blood glucose were measured after an initial fast and subsequently after each of the four 24-hr periods of isonitrogenous feeding. The grade of PSE was assessed clinically and by the number connection test, BCAA concentrations were significantly lower during the glucose infusion than during fasting or the lipid infusion. PSE was significantly less with the lipid than with the glucose infusion. Trials testing the effect of infused BCAA must take account of the opposing effect on BCAA concentrations of simultaneous glucose infusion. A high lipid feed may have advantages in the short-term treatment of PSE. (Journal of Parenteral and Enteral Nutrition 12:457-461, 1988)

Journal of Parenteral and Enteral Nutrition, Vol. 12, No. 5, 457-461 (1988)
DOI: 10.1177/0148607188012005457
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
L. Marsano and C. J. Mcclain
Review: Nutrition and Alcoholic Liver Disease
JPEN J Parenter Enteral Nutr, May 1, 1991; 15(3): 337 - 344.
[Abstract] [PDF]