Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Parenteral and Enteral Nutrition
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Barat, A. C.
Right arrow Articles by Mcintosh, N. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Barat, A. C.
Right arrow Articles by Mcintosh, N. L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Effect of Amino Acid Solutions on Total Nutrient Admixture Stability

Agnes C. Barat, M.S.

California State University, Long Beach. California, Community Alimentation Services, Chatsworth, California, Alpha Therapeutic Corporation, Los Angeles, California

Kathleen Harrie, M.S.

California State University, Long Beach. California, Community Alimentation Services, Chatsworth, California, Alpha Therapeutic Corporation, Los Angeles, California

Mary Jacob, PH.D.

California State University, Long Beach. California, Community Alimentation Services, Chatsworth, California, Alpha Therapeutic Corporation, Los Angeles, California

Thomas G. Diamantidis, PHARM.D.

California State University, Long Beach. California, Community Alimentation Services, Chatsworth, California, Alpha Therapeutic Corporation, Los Angeles, California

Norma L. Mcintosh, PH.D., R.D.

California State University, Long Beach. California, Community Alimentation Services, Chatsworth, California, Alpha Therapeutic Corporation, Los Angeles, California

The stability of total nutrient admixture (TNA) systems containing a soybean oil emulsion (Soyacal) has been reported with only one amino acid (AA) solution. This study was conducted to compare the physical stability of 10 TNA systems varied only by the AA solution used. All systems contained electrolytes, vitamins, trace elements, and heparin. The volume ratios of AA, dextrose 70% and lipid emulsion 20% were 1:1:1. Solutions were stored at 4°C for 14 days and then held at ambient temperature for an additional 4 days. Each TNA was serially analyzed on days 0, 1, 3, 5, 7, 14, 15, 16, 17, and 18 for gross visual appearance, pH, osmolality, mean particle diameter, and particle size distribution. The AA solutions evaluated include: Travasol 8.5% and 10%; Aminosyn 8.5% and 10%, Aminosyn RF 5.2%; FreAmine III 8.5% and 10%; FreAmine HBC 6.9%; HepatAmine 8.0%; and NephrAmine 5.4%. The pH values of the Aminosyn solutions were lower than those of other products; however, the pH values of all TNA systems were >5.7, which supported particle stability. The osmolality was not affected by the AA solutions. Based upon particle size distribution, 95% of all particles were <0.608 µm in diameter, with means ranging from 0.286 µm to 0.309 µm. The largest particle observed by light microscopy was 6.9 µm. These data indicate that TNA systems prepared with the 10 AA solutions and Soyacal 20% are physically stable. (Journal of Parenteral and Enteral Nutrition 11:384-388, 1987)

Journal of Parenteral and Enteral Nutrition, Vol. 11, No. 4, 384-388 (1987)
DOI: 10.1177/0148607187011004384
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?