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Effect of Enteral Nutrition on Human Pancreatic Secretions

Department of Surgery, Duke University Medical Center, Durham, North Carolina

Joann Davey-Mccrae, M.S., R.D.

Department of Surgery, Duke University Medical Center, Durham, North Carolina

Phyllis J. Snyder, B.A.

Department of Surgery, Duke University Medical Center, Durham, North Carolina

The influence on pancreatic secretion of four enteral feeding products was evaluated in a unique patient with an isolated duodenal fistula for whom enteral feeding access was obtained via a gastrostomy with a small Silastic catheter passed through the gastrostomy and through a surgically created gastrojejunostomy. The patient was totally supported by intravenous nutrition during the study. Each enteral feeding solution was administered at full strength at 50 ml/hr for 2 days with a 24-hr collection of pancreatic secretions by the duodenal cutaneous fistula taken on the second day Infusion of the enteral feeding solutions did not alter volume of fistula drainage. All solutions decreased bicarbonate and amylase secretion but increased lipase and total nitrogen excretion. From this study, it would appear reasonable to administer Vivonex HN and Criticare HN via the jejunum in patients with pancreatic disease, whereas Osmolite would appear less satisfactory, due to its much stronger stimulation of lipase secretion. (Journal of Parenteral and Enteral Nutrition 11: 302-304, 1987)

Journal of Parenteral and Enteral Nutrition, Vol. 11, No. 3, 302-304 (1987)
DOI: 10.1177/0148607187011003302


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