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Journal of Parenteral and Enteral Nutrition
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*Dietary Fats
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Journal Article

Pancreatic enzyme secretion during intravenous fat infusion

GP Burns and TA Stein

The nutritional support of patients with pancreatic and high gastrointestinal fistulas and severe pancreatitis frequently involves intravenous fat infusion. There are conflicting reports on the effect of intravenous fat on pancreatic exocrine secretion. In 10 dogs with chronic pancreatic fistulas, pancreatic juice was collected during secretin (n = 10) or secretin + cholecystokinin (n = 4) stimulation, with and without intravenous fat infusion (5 g/hr). The hormonal-stimulated secretion of lipase, amylase, trypsin, total protein, bicarbonate, and water was unchanged during fat infusion. This study supports the use of intravenous fat as a nutritional source when it is desirable to avoid stimulation of the pancreas.

Journal of Parenteral and Enteral Nutrition, Vol. 11, No. 1, 60-62 (1987)
DOI: 10.1177/014860718701100160
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