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Journal of Parenteral and Enteral Nutrition
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Serum Vitamin E Levels in Very Low-Birth Weight Infants Receiving Vitamin E in Parenteral Nutrition Solutions

Victoria Devito, M.D.

Department of Pediatrics, Oregon Health Sciences University, Portland, Oregon

John W. Reynolds, M.D.

Department of Pediatrics, Oregon Health Sciences University, Portland, Oregon

Gerda I. Benda, M.D.

Department of Pediatrics, Oregon Health Sciences University, Portland, Oregon

Christina Carlson, B.S.

Department of Pediatrics, Oregon Health Sciences University, Portland, Oregon

Serum vitamin E levels were measured in 17 very low-birth weight infants in the first 2 wk of life, before and after the institution of intravenous vitamin E supplementation in a dosage of 4.5 mg/day, as a component of MVI Pediatric multivitamin preparation. Serum vitamin E levels were 0.22 ± 0.16 (SD) mg/dl before supplementation, and rose to 2.55 ± 0.65 (SD) mg/dl in nine infants more than 899 g birth weight, and rose to 3.68 ± 0.70 (SD) mg/dl in six infants less than 900 g at birth. These postsupplementation serum vitamin E levels are in the range in which a reduction of incidence or severity of retinopathy of prematurity and intraventricular cerebral hemorrhage has been reported by others. No toxic effects of the preparation or of the increased vitamin E levels were found. (Journal of Parenteral and Enteral Nutrition 10:63-65, 1986)

Journal of Parenteral and Enteral Nutrition, Vol. 10, No. 1, 63-65 (1986)
DOI: 10.1177/014860718601000163
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This article has been cited by other articles:


Home page
 JPEN J Parenter Enteral NutrHome page
F.J. Kelly and G.L.J. Sutton
Plasma and Red Blood Cell Vitamin E Status of Patients on Total Parenteral Nutrition
JPEN J Parenter Enteral Nutr, September 1, 1989; 13(5): 510 - 515.
[Abstract] [PDF]

Home page
 JPEN J Parenter Enteral NutrHome page
M. G. Macdonald, A. B. Fletcher, E. L. Johnson, R. L. Boeckx, P. R. Getson, and M. K. Miller
The Potential Toxicity to Neonates of Multivitamin Preparations Used in Parenteral Nutrition
JPEN J Parenter Enteral Nutr, March 1, 1987; 11(2): 169 - 171.
[Abstract] [PDF]